Quantitative analyses of empirical fitness landscapes

  title={Quantitative analyses of empirical fitness landscapes},
  author={Ivan G. Szendro and Martijn F. Schenk and Jasper Franke and Joachim H A Krug and J. Arjan G.M. de Visser},
  journal={Journal of Statistical Mechanics: Theory and Experiment},
The concept of a fitness landscape is a powerful metaphor that offers insight into various aspects of evolutionary processes and guidance for the study of evolution. Until recently, empirical evidence on the ruggedness of these landscapes was lacking, but since it became feasible to construct all possible genotypes containing combinations of a limited set of mutations, the number of studies has grown to a point where a classification of landscapes becomes possible. The aim of this review is to… 

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