Quantitative Targeted Proteomics for Membrane Transporter Proteins: Method and Application

@article{Qiu2014QuantitativeTP,
  title={Quantitative Targeted Proteomics for Membrane Transporter Proteins: Method and Application},
  author={Xi Qiu and Hui Zhang and Yurong Lai},
  journal={The AAPS Journal},
  year={2014},
  volume={16},
  pages={714-726}
}
Although global proteomics has shown promise for discovery of many new proteins, biomarkers, protein modifications, and polymorphisms, targeted proteomics is emerging in the proteomics research field as a complement to untargeted shotgun proteomics, particularly when a determined set of low-abundance functional proteins need to be measured. The function and expression of proteins related to drug absorption, distribution, metabolism, and excretion (ADME) such as cytochrome P450 enzymes and… CONTINUE READING
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