Quantitative Structure‐Activity Relationships of Perfluorinated Hetero‐Hydrocarbons as Potential Respiratory Media: Application to Oxygen Solubility, Partition Coefficient, Viscosity, Vapor Pressure, and Density

@article{Gabriel1996QuantitativeSR,
  title={Quantitative Structure‐Activity Relationships of Perfluorinated Hetero‐Hydrocarbons as Potential Respiratory Media: Application to Oxygen Solubility, Partition Coefficient, Viscosity, Vapor Pressure, and Density},
  author={J. Gabriel and T. F. Miller and M. Wolfson and T. Shaffer},
  journal={ASAIO Journal},
  year={1996},
  volume={42},
  pages={968–973}
}
&NA; It has been extensively reported that liquid‐assisted ventilation, using inert perfluorocarbon liquids (PFCs), can reduce interfacial surface tension and allow for improved ventilation at decreased alveolar pressures. PFCs are bioinert, minimally absorbed, and have no deleterious histologic, cellular, or biochemical effects when used as respiratory media. Although several types of PFCs have been characterized, a select few are considered to be compatible with life. Compatibility is often… Expand
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