Quantitative Proteomic Analysis of the Human Nucleolus.

  title={Quantitative Proteomic Analysis of the Human Nucleolus.},
  author={Dalila Bensaddek and Armel Nicolas and Angus I. Lamond},
  journal={Methods in molecular biology},
Recent years have witnessed spectacular progress in the field of mass spectrometry (MS)-based quantitative proteomics, including advances in instrumentation, chromatography, sample preparation methods, and experimental design for multidimensional analyses. It is now possible not only to identify most of the protein components of a cell proteome in a single experiment, but also to describe additional proteome dimensions, such as protein turnover rates, posttranslational modifications, and… CONTINUE READING