Quantitative MRI using T1ρ and T2 in human osteoarthritic cartilage specimens: correlation with biochemical measurements and histology.

@article{Li2011QuantitativeMU,
  title={Quantitative MRI using T1ρ and T2 in human osteoarthritic cartilage specimens: correlation with biochemical measurements and histology.},
  author={Xiaojuan Li and Jonathan Cheng and Katrina J Lin and Ehsan Saadat and Radu I. Bolbos and Bj{\"o}rn Jobke and Michael D. Ries and Andrew E Horvai and Thomas M. Link and Sharmila Majumdar},
  journal={Magnetic resonance imaging},
  year={2011},
  volume={29 3},
  pages={324-34}
}
PURPOSE A direct correlation between T(1ρ), T(2) and quantified proteoglycan and collagen contents in human osteoarthritic cartilage has yet to be documented. We aimed to investigate the orientation effect on T(1ρ) and T(2) values in human osteoarthritic cartilage and to quantify the correlation between T(1ρ), T(2) vs. biochemical composition and histology in human osteoarthritic cartilage. MATERIALS AND METHODS Thirty-three cartilage specimens were collected from patients who underwent total… CONTINUE READING

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