Quantitative Imaging of Transcription in Living Drosophila Embryos Links Polymerase Activity to Patterning

@article{Garcia2013QuantitativeIO,
  title={Quantitative Imaging of Transcription in Living Drosophila Embryos Links Polymerase Activity to Patterning},
  author={Hernan G. Garcia and Mikhail Tikhonov and Albert Yu-Min Lin and Thomas Gregor},
  journal={Current Biology},
  year={2013},
  volume={23},
  pages={2140-2145}
}
Spatiotemporal patterns of gene expression are fundamental to every developmental program. The resulting macroscopic domains have been mainly characterized by their levels of gene products. However, the establishment of such patterns results from differences in the dynamics of microscopic events in individual cells such as transcription. It is unclear how these microscopic decisions lead to macroscopic patterns, as measurements in fixed tissue cannot access the underlying transcriptional… CONTINUE READING
BETA

From This Paper

Figures, tables, and topics from this paper.

Explore Further: Topics Discussed in This Paper

Citations

Publications citing this paper.
SHOWING 1-10 OF 62 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 22 REFERENCES

Similar Papers

Loading similar papers…