Quantitative Expression of C-Type Lectin Receptors in Humans and Mice

  title={Quantitative Expression of C-Type Lectin Receptors in Humans and Mice},
  author={Maciej Lech and Heni Eka Susanti and C R{\"o}mmele and Regina Groebmayr and Roman G{\"u}nthner and Hans-Joachim Anders},
  booktitle={International journal of molecular sciences},
C-type lectin receptors and their adaptor molecules are involved in the recognition of glycosylated self-antigens and pathogens. However, little is known about the species- and organ-specific expression profiles of these molecules. We therefore determined the mRNA expression levels of Dectin-1, MR1, MR2, DC-SIGN, Syk, Card-9, Bcl-10, Malt-1, Src, Dec-205, Galectin-1, Tim-3, Trem-1, and DAP-12 in 11 solid organs of human and mice. Mouse organs revealed lower mRNA levels of most molecules… CONTINUE READING


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