Quantitative Evaluation of the Enhanced Permeability and Retention (EPR) Effect.

@article{Russell2017QuantitativeEO,
  title={Quantitative Evaluation of the Enhanced Permeability and Retention (EPR) Effect.},
  author={Luisa M. Russell and Charlene M. Dawidczyk and Peter C. Searson},
  journal={Methods in molecular biology},
  year={2017},
  volume={1530},
  pages={247-254}
}
Quantitative evaluation of nanoparticle delivery to a tumor site can be invaluable for cross-platform comparison, a consideration not currently taken into account by many in the field of cancer nanomedicine (Dawidczyk et al., Front Chem 2:69, 2014). Standardization of measured parameters and experimental design will facilitate nanoparticle design and understanding in the field. Here, we present a broadly applicable in vivo protocol for preclinical trials of nanomedicines, including… CONTINUE READING