Quantitative Dynamic Modelling of the Gene Regulatory Network Controlling Adipogenesis

Abstract

Gene regulatory networks (GRNs) coherently coordinate the expressions of genes and control the behaviors of cellular systems. The complexity in modeling a quantitative GRN usually results from inaccurate parameter estimation, which is mostly due to small sample sizes. For better modeling of GRNs, we have designed a small-sample iterative optimization… (More)
DOI: 10.1371/journal.pone.0110563

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@inproceedings{Wang2014QuantitativeDM, title={Quantitative Dynamic Modelling of the Gene Regulatory Network Controlling Adipogenesis}, author={Yin Wang and Rudong Li and Chunguang Ji and Shuliang Shi and Yufan Cheng and Hong Sun and Yixue Li and Ben D. MacArthur}, booktitle={PloS one}, year={2014} }