Quantitative Determination of three Angiotensin-II-receptor Antagonists in Presence of Hydrochlorothiazide by RP-HPLC in their Tablet Preparations

@inproceedings{Hafez2013QuantitativeDO,
  title={Quantitative Determination of three Angiotensin-II-receptor Antagonists in Presence of Hydrochlorothiazide by RP-HPLC in their Tablet Preparations },
  author={Hany Mohammed Hafez and Abdullah Ahmed Elshanawane and Lobna Mohammed Abdelaziz and Magda Mohammed Kamal},
  booktitle={Iranian journal of pharmaceutical research : IJPR},
  year={2013}
}
Losartan potassium, Valsartan , Telmisartan and Irbesartan are angiotensin-II-receptor antagonists (ARA II) group which used in treatment of hypertension alone or in combination with other drugs mainly Hydrochlorothiazide. RP- HPLC method was developed for the assay of three angiotensin-II-receptor antagonists (ARA-IIs) in presence of Hydrochlorothiazide. The method was performed by reversed phase high performance liquid chromatography using a mobile phase which is consisted of 0.025 M… CONTINUE READING

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