Quantitative Analysis Reveals Expansion of Human Hematopoietic Repopulating Cells After Short-term Ex Vivo Culture

@article{Bhatia1997QuantitativeAR,
  title={Quantitative Analysis Reveals Expansion of Human  Hematopoietic Repopulating Cells After Short-term Ex Vivo Culture },
  author={Mickie Bhatia and Dominique Bonnet and Ursula Kapp and Jean C. Y. Wang and Barbara Murdoch and John E Dick},
  journal={The Journal of Experimental Medicine},
  year={1997},
  volume={186},
  pages={619 - 624}
}
Ex vivo culture of human hematopoietic cells is a crucial component of many therapeutic applications. Although current culture conditions have been optimized using quantitative in vitro progenitor assays, knowledge of the conditions that permit maintenance of primitive human repopulating cells is lacking. We report that primitive human cells capable of… CONTINUE READING