Quantitation of telomerase activity in hepatocellular carcinoma: a possible aid for a prediction of recurrent diseases in the remnant liver.

@article{Suda1998QuantitationOT,
  title={Quantitation of telomerase activity in hepatocellular carcinoma: a possible aid for a prediction of recurrent diseases in the remnant liver.},
  author={Takafumi Suda and Osamu Isokawa and Yutaka Aoyagi and Minoru Nomoto and Kazuhiro Tsukada and Toshihiro Shimizu and Yoshihiko Suzuki and Akira Naito and Hisato Igarashi and Masahiko Yanagi and Teruyuki Takahashi and Hitoshi Asakura},
  journal={Hepatology},
  year={1998},
  volume={27 2},
  pages={402-6}
}
Because telomerase activity is necessary for cell immortality and probably associated with tumor progression, we have evaluated a possible aid for quantitation of the activity to predict intrahepatic recurrences after surgery in patients with hepatocellular carcinoma (HCC). HCC tissues obtained by surgical resection from 20 patients were studied. Telomerase activity was expressed as peaks with a periodicity through a fluorescence-based telomeric repeat amplification protocol using an… CONTINUE READING