Quantitation of serum free light chains in combination with protein electrophoresis and clinical information for diagnosing multiple myeloma in a general hospital population.

@article{Piehler2008QuantitationOS,
  title={Quantitation of serum free light chains in combination with protein electrophoresis and clinical information for diagnosing multiple myeloma in a general hospital population.},
  author={Armin P. Piehler and Nina Gulbrandsen and Peter B Kierulf and Petter Urdal},
  journal={Clinical chemistry},
  year={2008},
  volume={54 11},
  pages={1823-30}
}
BACKGROUND Serum free light chain (SFLC) measurements have recently come into use as an aid for diagnosing monoclonal gammopathy. We evaluated SFLC measurements in combination with serum protein electrophoresis (SPE) and clinical information for diagnosing multiple myeloma (MM) in a hospital population. METHODS We measured SFLCs in 3818 sera received for SPE over a 1-year period when patient symptoms or biochemical findings suggested myeloma-related tissue damage (n = 1067). We reviewed SPE… CONTINUE READING

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