Quantitation of doxapram in blood, plasma and urine.


Methods for the quantitation of doxapram in blood, plasma and urine have been developed. Following extraction, gas-liquid chromatography was used to separate doxapram from basic metabolites. Doxapram was detected by mass spectrometry for blood and plasma assays, and by flame ionisation for urine assays. The limit of reliable quantitation in blood and plasma… (More)


Cite this paper

@article{Nichol1980QuantitationOD, title={Quantitation of doxapram in blood, plasma and urine.}, author={Heather Nichol and John H. Vine and Janelle V Thomas and Richard Moore}, journal={Journal of chromatography}, year={1980}, volume={182 2}, pages={191-200} }