Quantitation of benzodiazepines in blood and urine using gas chromatography-mass spectrometry (GC-MS).


The benzodiazepine assay utilizes gas chromatography-mass spectrometry (GC-MS) for the analysis of diazepam, nordiazepam, oxazepam, temazepam, lorazepam, alpha-hydroxyalprazolam, and alpha-hydroxytriazolam in blood and urine. A separate assay is employed for the analysis of alprazolam. Prior to solid phase extraction, urine specimens are subjected to enzyme… (More)
DOI: 10.1007/978-1-60761-459-3_8


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