Quantitation of basement membrane collagen degradation by living tumor cells in vitro.

Abstract

In order to study the mechanism of tumor cell invasion of basement membranes, a new method has been developed to quantify basement membrane (type IV) collagen degradation by living tumor cells. Tumor cells are inoculated into 16-mm tissue culture wells coatd with biosynthetically [14C]proline-labeled type IV collagen. Soluble degradation products are… (More)

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Cite this paper

@article{Garbisa1980QuantitationOB, title={Quantitation of basement membrane collagen degradation by living tumor cells in vitro.}, author={Spiridione Garbisa and Kara Kniska and K. Tryggvason and Carol Foltz and Lance A. Liotta}, journal={Cancer letters}, year={1980}, volume={9 4}, pages={359-66} }