Quantitation of antibody uptake in spontaneous metastases.


A procedure of high resolution quantitative autoradiography was established and tested in the murine ESb-Mp lymphoma system. Using 125I-labelled antibody 12-15A, liver metastases with diameters down to 100 microns were identified and intralesional radioiodine accumulation was assessed as % injected dose (iD) g-1. Uptake was found to be highest in… (More)


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