Quantitation and localization of matrix metalloproteinases and their inhibitors in human carotid endarterectomy tissues.

@article{Choudhary2006QuantitationAL,
  title={Quantitation and localization of matrix metalloproteinases and their inhibitors in human carotid endarterectomy tissues.},
  author={Salman Choudhary and Catherine L Higgins and Iou Yih Chen and Michael Reardon and G. J. G. Lawrie and G. Wesley Vick and Christof Karmonik and David P. Via and Joel D. Morrisett},
  journal={Arteriosclerosis, thrombosis, and vascular biology},
  year={2006},
  volume={26 10},
  pages={2351-8}
}
BACKGROUND Matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) play a central role in arterial wall remodeling, affecting stability of fibrous caps covering atherosclerotic plaques. The objective of this study was to determine the spatial distribution of TIMP mass and MMP mass and activity of carotid endarterectomy (CEA) tissues and relate it to… CONTINUE READING