Quantifying transient 3D dynamical phenomena of single mRNA particles in live yeast cell measurements.

@article{Calderon2013QuantifyingT3,
  title={Quantifying transient 3D dynamical phenomena of single mRNA particles in live yeast cell measurements.},
  author={Christopher P. Calderon and Michael Allen Thompson and Jason M. Casolari and Alexander M. Wyglinski and W E Moerner},
  journal={The journal of physical chemistry. B},
  year={2013},
  volume={117 49},
  pages={15701-13}
}
Single-particle tracking (SPT) has been extensively used to obtain information about diffusion and directed motion in a wide range of biological applications. Recently, new methods have appeared for obtaining precise (10s of nm) spatial information in three dimensions (3D) with high temporal resolution (measurements obtained every 4 ms), which promise to more accurately sense the true dynamical behavior in the natural 3D cellular environment. Despite the quantitative 3D tracking information… CONTINUE READING
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