Quantifying traction stresses in adherent cells.

  title={Quantifying traction stresses in adherent cells.},
  author={Casey M. Kraning-Rush and Shawn P. Carey and Joseph P. Califano and Cynthia A. Reinhart-King},
  journal={Methods in cell biology},
Contractile force generation plays a critical role in cell adhesion, migration, and extracellular matrix reorganization in both 2D and 3D environments. Characterization of cellular forces has led to a greater understanding of cell migration, cellular mechanosensing, tissue formation, and disease progression. Methods to characterize cellular traction stresses now date back over 30 years, and they have matured from qualitative comparisons of cell-mediated substrate movements to high-resolution… CONTINUE READING

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