Quantifying the variation in the effective population size within a genome.

@article{Gossmann2011QuantifyingTV,
  title={Quantifying the variation in the effective population size within a genome.},
  author={Toni I Gossmann and Megan Woolfit and Adam Eyre-Walker},
  journal={Genetics},
  year={2011},
  volume={189 4},
  pages={1389-402}
}
The effective population size (N(e)) is one of the most fundamental parameters in population genetics. It is thought to vary across the genome as a consequence of differences in the rate of recombination and the density of selected sites due to the processes of genetic hitchhiking and background selection. Although it is known that there is intragenomic variation in the effective population size in some species, it is not known whether this is widespread or how much variation in the effective… CONTINUE READING
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