Quantifying the cerebral metabolic rate of oxygen by combining diffuse correlation spectroscopy and time-resolved near-infrared spectroscopy.

@article{Verdecchia2013QuantifyingTC,
  title={Quantifying the cerebral metabolic rate of oxygen by combining diffuse correlation spectroscopy and time-resolved near-infrared spectroscopy.},
  author={Kyle Verdecchia and Mamadou Diop and Ting-Yim Lee and Keith S. St. Lawrence},
  journal={Journal of biomedical optics},
  year={2013},
  volume={18 2},
  pages={27007}
}
Preterm infants are highly susceptible to ischemic brain injury; consequently, continuous bedside monitoring to detect ischemia before irreversible damage occurs would improve patient outcome. In addition to monitoring cerebral blood flow (CBF), assessing the cerebral metabolic rate of oxygen (CMRO2) would be beneficial considering that metabolic thresholds can be used to evaluate tissue viability. The purpose of this study was to demonstrate that changes in absolute CMRO2 could be measured by… CONTINUE READING