Quantifying signal changes in nano-wire based biosensors.

  title={Quantifying signal changes in nano-wire based biosensors.},
  author={Luca De Vico and Martin H S\orensen and Lars Fogh Iversen and David M. Rogers and Brian S S\orensen and Mads Brandbyge and Jesper Nyg̊ard and K L Martinez and Jan H. Jensen},
  volume={3 2},
In this work, we present a computational methodology for predicting the change in signal (conductance sensitivity) of a nano-BioFET sensor (a sensor based on a biomolecule binding another biomolecule attached to a nano-wire field effect transistor) upon binding its target molecule. The methodology is a combination of the screening model of surface charge sensors in liquids developed by Brandbyge and co-workers [Sørensen et al., Appl. Phys. Lett., 2007, 91, 102105], with the PROPKA method for… CONTINUE READING

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