Quantifying raft proteins in neonatal mouse brain by 'tube-gel' protein digestion label-free shotgun proteomics

@article{Yu2007QuantifyingRP,
  title={Quantifying raft proteins in neonatal mouse brain by 'tube-gel' protein digestion label-free shotgun proteomics},
  author={Hongwei Yu and Bassam T. Wakim and Man Li and Brian D. Halligan and G. Stephen Tint and Shailendra B Patel},
  journal={Proteome Science},
  year={2007},
  volume={5},
  pages={17 - 17}
}
The low concentration and highly hydrophobic nature of proteins in lipid raft samples present significant challenges for the sensitive and accurate proteomic analyses of lipid raft proteins. Elimination of highly enriched lipids and interfering substances from raft samples is generally required before mass spectrometric analyses can be performed, but these procedures often lead to excessive protein loss and increased sample variability. For accurate analyses of the raft proteome, simplified… CONTINUE READING

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A New Algorithm Using Cross - Assignment for Label - Free Quantitation with LC - LTQ - FT MS

  • S Wienkoop, E Larrainzar, M Niemann, EM Gonzalez, U Lehmann, W Weckwerth
  • J Proteome Res
  • 2007

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