Quantifying radiation therapy-induced brain injury with whole-brain proton MR spectroscopy: initial observations.


PURPOSE To quantify the extent of neuronal cell loss imparted to the brain by means of radiation therapy through the decline of the amino acid derivative N-acetylaspartate (NAA) by using proton (hydrogen 1) magnetic resonance (MR) spectroscopy. MATERIALS AND METHODS Proton MR spectroscopy in a clinical MR imager was used to ascertain the amount of whole… (More)


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