Quantifying pulsed electric field-induced membrane nanoporation in single cells.

@article{Moen2016QuantifyingPE,
  title={Quantifying pulsed electric field-induced membrane nanoporation in single cells.},
  author={Erick K. Moen and Bennett L. Ibey and Hope T. Beier and Andrea M. Armani},
  journal={Biochimica et biophysica acta},
  year={2016},
  volume={1858 11},
  pages={
          2795-2803
        }
}
Plasma membrane disruption can trigger a host of cellular activities. One commonly observed type of disruption is pore formation. Molecular dynamic (MD) simulations of simplified lipid membrane structures predict that controllably disrupting the membrane via nano-scale poration may be possible with nanosecond pulsed electric fields (nsPEF). Until recently, researchers hoping to verify this hypothesis experimentally have been limited to measuring the relatively slow process of fluorescent… CONTINUE READING
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