Quantifying interictal metabolic activity in human temporal lobe epilepsy.

  title={Quantifying interictal metabolic activity in human temporal lobe epilepsy.},
  author={Thomas R. Henry and John C. Mazziotta and Jerome Engel and Peter D Christenson and John X. Zhang and Michael E. Phelps and David E. Kuhl},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  volume={10 5},
The majority of patients with complex partial seizures of unilateral temporal lobe origin have interictal temporal hypometabolism on [18F]fluorodeoxyglucose positron emission tomography (FDG PET) studies. Often, this hypometabolism extends to ipsilateral extratemporal sites. The use of accurately quantified metabolic data has been limited by the absence of an equally reliable method of anatomical analysis of PET images. We developed a standardized method for visual placement of anatomically… CONTINUE READING
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