Quantifying estrogen and progesterone receptor expression in breast cancer by digital imaging.

@article{Szeszel2005QuantifyingEA,
  title={Quantifying estrogen and progesterone receptor expression in breast cancer by digital imaging.},
  author={Monika K. Szeszel and Cameron L Crisman and Lauren E. Crow and Steven McMullen and Jacqueline M Major and Loki Natarajan and Abu Saquib and James R. Feramisco and Linda M. Wasserman},
  journal={The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society},
  year={2005},
  volume={53 6},
  pages={753-62}
}
Developments in digital imaging and fluorescent microscopy provide a new method and opportunities for quantification of protein expression in human tissue. Archived collections of paraffin-embedded tumors can be used to study the relationship between quantitative differences in protein expression in tumors and patient outcome. In this report we describe the use of a DeltaVision Restoration deconvolution microscope, combined with fluorescent immunohistochemistry, to obtain reproducible and… CONTINUE READING

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