Quantifying brain iron deposition in patients with Parkinson's disease using quantitative susceptibility mapping, R2 and R2.

@article{Barbosa2015QuantifyingBI,
  title={Quantifying brain iron deposition in patients with Parkinson's disease using quantitative susceptibility mapping, R2 and R2.},
  author={Jeam Haroldo O. Barbosa and Antonio Carlos dos Santos and V{\'i}tor Tumas and Manju Liu and Weili Zheng and E. Mark Haacke and Carlos E. G. Salmon},
  journal={Magnetic resonance imaging},
  year={2015},
  volume={33 5},
  pages={559-65}
}
PURPOSE To evaluate the sensitivity and specificity of quantitative magnetic resonance (MR) iron mapping including R2, R2* and magnetic susceptibility to differentiate patients with Parkinson's disease (PD) from healthy controls. MATERIALS AND METHODS Thirty (30) healthy controls (HC) (64±7years old) and 20 patients with idiopathic PD (66±8years old) were studied using a 3T MR imaging scanner. R2 maps were generated from GRASE sequence while R2*, and quantitative susceptibility mapping (QSM… CONTINUE READING

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