Quantifying and documenting prior beliefs in clinical trials.

  title={Quantifying and documenting prior beliefs in clinical trials.},
  author={Kathryn Chaloner and Frank S Rhame},
  journal={Statistics in medicine},
  volume={20 4},
Collecting and documenting subjective prior beliefs from knowledgeable clinicians about the potential results of a clinical trial has many advantages. Two large trials of prophylactic treatments in an HIV-positive population are used as examples. The trials recruited patients of primary care physicians and compared treatments which were in use in clinical practice. Opinions about these trials were elicited from 58 practising HIV clinicians. It is shown how the documented opinions can be used to… CONTINUE READING

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