Quantifying Microstructure in Fiber Crossings with Diffusional Kurtosis

  title={Quantifying Microstructure in Fiber Crossings with Diffusional Kurtosis},
  author={Michael Ankele and T. Schultz},
Diffusional Kurtosis Imaging DKI is able to capture non-Gaussian diffusion and has become a popular complement to the more traditional Diffusion Tensor Imaging DTI. In this paper, we demonstrate how strongly the presence of fiber crossings and the exact crossing angle affect measures from diffusional kurtosis, limiting their interpretability as indicators of tissue microstructure. We alleviate this limitation by modeling fiber crossings with a mixture of cylindrically symmetric kurtosis models… Expand
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