Quantifying Material Properties of Cell Monolayers by Analyzing Integer Topological Defects.

  title={Quantifying Material Properties of Cell Monolayers by Analyzing Integer Topological Defects.},
  author={Carles Blanch-Mercader and Pau Guillamat and Aur{\'e}lien Roux and Karsten Kruse},
  journal={Physical review letters},
  volume={126 2},
In developing organisms, internal cellular processes generate mechanical stresses at the tissue scale. The resulting deformations depend on the material properties of the tissue, which can exhibit long-ranged orientational order and topological defects. It remains a challenge to determine these properties on the time scales relevant for developmental processes. Here, we build on the physics of liquid crystals to determine material parameters of cell monolayers. Specifically, we use a… 

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