Quantifying EGJ morphology and relaxation with high-resolution manometry: a study of 75 asymptomatic volunteers.

  title={Quantifying EGJ morphology and relaxation with high-resolution manometry: a study of 75 asymptomatic volunteers.},
  author={John E. Pandolfino and Sudip Kumar Ghosh and Qing Zhang and Andrew Jarosz and Nimeesh K. Shah and Peter J. Kahrilas},
  journal={American journal of physiology. Gastrointestinal and liver physiology},
  volume={290 5},
Our aim was to define normal esophagogastric junction (EGJ) morphology and relaxation characteristics using high-resolution manometry (HRM). To this end, 75 asymptomatic controls underwent HRM with a solid-state manometric assembly incorporating 36 circumferential sensors spaced at 1-cm intervals positioned to record from the hypopharynx to the stomach. Ten 5-ml water swallows were obtained. EGJ relaxation was quantified by 1) nadir pressure, 2) the lowest 3-s mean residual pressure after… 

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All values are expressed as means (SD) UESB, bottom of the upper esophageal sphincter; EGJT, top of the EGJ; EGJmax, maximal EGJ pressure; EGJB bottom of the EGJ

  • All values are expressed as means (SD) UESB, bottom of the upper esophageal sphincter; EGJT, top of the EGJ; EGJmax, maximal EGJ pressure; EGJB bottom of the EGJ