Quantification of viral DNA during HIV-1 infection: A review of relevant clinical uses and laboratory methods.


Effective antiretroviral therapy usually leads to undetectable HIV-1 RNA in the plasma. However, the virus persists in some cells of infected patients as various DNA forms, both integrated and unintegrated. This reservoir represents the greatest challenge to the complete cure of HIV-1 infection and its characteristics highly impact the course of the disease… (More)
DOI: 10.1016/j.patbio.2014.07.007

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