Quantification of tumour vasculature and hypoxia by immunohistochemical staining and HbO2 saturation measurements

@inproceedings{Fenton1999QuantificationOT,
  title={Quantification of tumour vasculature and hypoxia by immunohistochemical staining and HbO2 saturation measurements},
  author={Bruce Miles Fenton and Scott F. Paoni and Jerry Aik Chong. Lee and Cameron J. Koch and Edith M. Lord},
  booktitle={British Journal of Cancer},
  year={1999}
}
SummaryDespite the possibility that tumour hypoxia may limit radiotherapeutic response, the underlying mechanisms remain poorly understood. A new methodology has been developed in which information from several sophisticated techniques is combined and analysed at a microregional level. First, tumour oxygen availability is spatially defined by measuring intravascular blood oxygen saturations (HbO2) cryospectrophotometrically in frozen tumour blocks. Second, hypoxic development is quantified in… CONTINUE READING
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