Quantification of the proliferation index of human dermal fibroblast cultures with the ArrayScan high-content screening reader.

@article{Gasparri2005QuantificationOT,
  title={Quantification of the proliferation index of human dermal fibroblast cultures with the ArrayScan high-content screening reader.},
  author={Fabio Gasparri and Mariangela Mariani and Francesco Sola and Arturo Galvani},
  journal={Drug discovery today},
  year={2005},
  volume={Suppl},
  pages={31-42}
}
High-throughput cell-based assays are becoming a powerful approach in the drug discovery process. The ArrayScan high-content screening (HCS) reader is a cytometer based on a fully automated fluorescence microscope that is able to obtain quantitative information on the intensity and localization of fluorescence signals within single cells over a wide cell population. The aim of this work was to set up an automated HCS multiparameter analysis for the quantification of the in vitro proliferation… CONTINUE READING

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