Quantification of the morphological reaction of platelets to aggregating agents and of its reversal by aggregation inhibitors.

@article{Born1978QuantificationOT,
  title={Quantification of the morphological reaction of platelets to aggregating agents and of its reversal by aggregation inhibitors.},
  author={Gustav V. R. Born and R. Dearnley and James G. Foulks and D. E. Sharp},
  journal={The Journal of physiology},
  year={1978},
  volume={280},
  pages={193-212}
}
1. In rabbit citrated platelet-rich plasma, the changes in shape of the platelets produced by adenosine diphosphate (ADP) or 5-hydroxytryptamine (5-HT) were observed by photometric and volumetric techniques and by measurements of platelet images on electron micrographs either directly or with an image analysing computer. This permitted the indirect manifestations of the shape changes to be correlated with the morphological features responsible for them, i.e. transformation of disks to more… CONTINUE READING

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