Quantification of the initial decline of serum hepatitis C virus RNA and response to interferon alfa.

@article{Zeuzem1998QuantificationOT,
  title={Quantification of the initial decline of serum hepatitis C virus RNA and response to interferon alfa.},
  author={Stefan Zeuzem and J H Lee and Andre Franke and Brigitte Ruester and Otto Pr{\"u}mmer and G{\"u}nter Herrmann and W. Kurt Roth},
  journal={Hepatology},
  year={1998},
  volume={27 4},
  pages={1149-56}
}
Although several virus- and host-related predictive factors for the response to interferon alfa (IFN-alpha) have been defined in patients with chronic hepatitis C, no pretreatment parameter can definitely predict the response to antiviral treatment. Assessment of the initial response by quantification of serum hepatitis C virus RNA before and 4 weeks after initiation of therapy may be a clinically applicable and reliable parameter to predict long-term response. Therefore, the aims of the… CONTINUE READING

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