Quantification of the heterogeneity of cerebral blood flow in vascular dementia

@article{Yoshikawa2003QuantificationOT,
  title={Quantification of the heterogeneity of cerebral blood flow in vascular dementia},
  author={Takuya Yoshikawa and Kenya Murase and Naohiko Oku and Kazuo Kitagawa and Masao Imaizumi and Masashi Takasawa and Piao Rishu and Kazuo Hashikawa and Takashi Nishikawa and Masatsugu Hori and Masayasu Matsumoto},
  journal={Journal of Neurology},
  year={2003},
  volume={250},
  pages={194-200}
}
Background: In vascular dementia (VaD), assessment of cerebral blood flow by single photon emission computed tomography (CBF SPECT) has been used to detect a patchy decrease of blood flow or a frontal reduction. In addition to reduced blood flow, the heterogeneous distribution of cerebral blood flow is often observed in VaD. However, no objective method to evaluate the heterogeneity has been established. In this study, we applied three-dimensional fractal analysis (3D-FA) to CBF SPECT images as… CONTINUE READING