Quantification of the cortical contribution to the NIRS signal over the motor cortex using concurrent NIRS-fMRI measurements

@article{Gagnon2012QuantificationOT,
  title={Quantification of the cortical contribution to the NIRS signal over the motor cortex using concurrent NIRS-fMRI measurements},
  author={Louis Gagnon and Meryem A. Y{\"u}cel and Mathieu Dehaes and Robert J. Cooper and Katherine L. Perdue and Juliette Selb and Theodore J. Huppert and Richard D. Hoge and David A. Boas},
  journal={NeuroImage},
  year={2012},
  volume={59},
  pages={3933-3940}
}
Near-Infrared Spectroscopy (NIRS) measures the functional hemodynamic response occurring at the surface of the cortex. Large pial veins are located above the surface of the cerebral cortex. Following activation, these veins exhibit oxygenation changes but their volume likely stays constant. The back-reflection geometry of the NIRS measurement renders the signal very sensitive to these superficial pial veins. As such, the measured NIRS signal contains contributions from both the cortical region… CONTINUE READING

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