Quantification of stratum corneum ceramides and lipid envelope ceramides in the hereditary ichthyoses.

@article{Paige1994QuantificationOS,
  title={Quantification of stratum corneum ceramides and lipid envelope ceramides in the hereditary ichthyoses.},
  author={David G. Paige and Nancy Morse-Fisher and John I. Harper},
  journal={The British journal of dermatology},
  year={1994},
  volume={131 1},
  pages={
          23-7
        }
}
Ceramides (sphingolipids) are the main polar lipids of the stratum corneum and play an important role in skin barrier function, cell adhesion and epidermal differentiation. In view of the function of ceramides in normal skin, this study aimed to assess their levels in patients with various types of hereditary ichthyosis, in which epidermal homeostasis is markedly abnormal. Stratum corneum samples were collected from 80 patients and 23 normal controls, and the intercellular and lipid envelope… CONTINUE READING
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