Quantification of population benefit in evaluation of biomarkers: practical implications for disease detection and prevention

@inproceedings{Li2014QuantificationOP,
  title={Quantification of population benefit in evaluation of biomarkers: practical implications for disease detection and prevention},
  author={Xiaohong Li and Patricia L. Blount and Brian J. Reid and Thomas L. Vaughan},
  booktitle={BMC Med. Inf. & Decision Making},
  year={2014}
}
BACKGROUND With the rapid development of "-omic" technologies, an increasing number of purported biomarkers have been identified for cancer and other diseases. The process of identifying those that are most promising and validating them for use at the population level for prevention and early detection is a critical next step in achieving significant health benefits. METHODS In this paper, we propose that in order to effectively translate biomarkers for practical clinical use, it is important… CONTINUE READING
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