Quantification of phthalocyanine concentration in rat tissue using laser-induced fluorescence spectroscopy.

@article{Panjehpour1993QuantificationOP,
  title={Quantification of phthalocyanine concentration in rat tissue using laser-induced fluorescence spectroscopy.},
  author={Masoud Panjehpour and R E Sneed and Donita L. Frazier and Mary Ann Barnhill and S F O'brien and W Harb and Bergein F. Overholt},
  journal={Lasers in surgery and medicine},
  year={1993},
  volume={13 1},
  pages={23-30}
}
Quantification of photosensitizer concentration in tissue should improve planning and outcome of photodynamic therapy. Laser-induced fluorescence (LIF) can be used to measure in vivo fluorescence of photosensitizers in tissue. This study was designed to determine if in vivo fluorescence intensity of chloroaluminum phthalocyanine tetrasulfonate correlates with its concentration in different rat tissues. Following LIF measurements, the animals were humanely euthanized and the concentration of… CONTINUE READING