Quantification of perfusion using bolus tracking magnetic resonance imaging in stroke: assumptions, limitations, and potential implications for clinical use.

@article{Calamante2002QuantificationOP,
  title={Quantification of perfusion using bolus tracking magnetic resonance imaging in stroke: assumptions, limitations, and potential implications for clinical use.},
  author={Fernando Calamante and David G. Gadian and Andrew Connelly},
  journal={Stroke},
  year={2002},
  volume={33 4},
  pages={1146-51}
}
BACKGROUND MR techniques have been very powerful in providing indicators of tissue perfusion, particularly in studies of cerebral ischemia. There is considerable interest in performing absolute perfusion measurements, with the aim of improving the characterization of tissue "at risk" of stroke. However, some important caveats relating to absolute measurements need to be taken into account. The purpose of this article is to discuss some of the issues involved and the potential implications for… CONTINUE READING
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