Quantification of nanoparticle uptake by cells using an unbiased sampling method and electron microscopy.


AIMS By randomly sampling a known fraction of a pellet of cultured cells, we have accurately estimated the mean number of 50 nm gold nanoparticles accumulated within a single cell. Cellular nanoparticle uptake was measured using a combination of stereological sampling techniques and transmission electron microscopy. MATERIALS & METHODS Nanoparticles were… (More)
DOI: 10.2217/nnm.11.70


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