Quantification of mycophenolate mofetil in human skin extracts using high-performance liquid chromatography-electrospray mass spectrometry.

Abstract

A sensitive and selective method for the quantification of mycophenolate mofetil and its active metabolite mycophenolic acid in different human skin layers after dermal administration is presented. The skin layers were separated after in vitro penetration experiments and a methanolic extraction was performed. Positive ion electrospray HPLC-MS in selected… (More)

Topics

Cite this paper

@article{Pltzer2001QuantificationOM, title={Quantification of mycophenolate mofetil in human skin extracts using high-performance liquid chromatography-electrospray mass spectrometry.}, author={Manuela Pl{\"a}tzer and Kathleen D Jahn and Julie Wohlrab and R. Neubert}, journal={Journal of chromatography. B, Biomedical sciences and applications}, year={2001}, volume={755 1-2}, pages={355-9} }