Quantification of metabolic limitations during recombinant protein production in Escherichia coli.

@article{Heyland2011QuantificationOM,
  title={Quantification of metabolic limitations during recombinant protein production in Escherichia coli.},
  author={Jan Heyland and Lars Mathias Blank and Andreas Schmid},
  journal={Journal of biotechnology},
  year={2011},
  volume={155 2},
  pages={178-84}
}
Escherichia coli is one of the major microorganisms for recombinant protein production because it has been best characterized in terms of molecular genetics and physiology, and because of the availability of various expression vectors and strains. The synthesis of proteins is one of the most energy consuming processes in the cell, with the result that cellular energy supply may become critical. Indeed, the so called metabolic burden of recombinant protein synthesis was reported to cause… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

Similar Papers

Loading similar papers…