Quantification of leukotriene B4 glucuronide in human urine.

@article{Mita2007QuantificationOL,
  title={Quantification of leukotriene B4 glucuronide in human urine.},
  author={H. Mita and Naomi Turikisawa and T. Yamada and M. Taniguchi},
  journal={Prostaglandins & other lipid mediators},
  year={2007},
  volume={83 1-2},
  pages={
          42-9
        }
}
We have developed a method for measuring leukotriene B4 glucuronide, a marker of systemic leukotriene B4 biosynthesis, in human urine. This method involves the separation of two positional isomers of leukotriene B4 glucuronide by high-performance liquid chromatography, followed by hydrolysis with beta-glucuronidase and then leukotriene B4 quantification by enzyme immunoassay after purification by high-performance liquid chromatography. One of two positional isomers of leukotriene B4 glucuronide… Expand
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