Quantification of human intestinal gene expression profiles using exfoliated colonocytes: a pilot study.

@article{Davidson2003QuantificationOH,
  title={Quantification of human intestinal gene expression profiles using exfoliated colonocytes: a pilot study.},
  author={Laurie A. Davidson and Joanne R. Lupton and Emil Miskovsky and Alan P. Fields and Robert S. Chapkin},
  journal={Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals},
  year={2003},
  volume={8 1},
  pages={51-61}
}
Early detection of colon cancer can result in a high cure rate; therefore, an accurate screening method is imperative. Adoption of non-invasive testing designed to reduce anxiety over colorectal cancer screening and improve early detection is highly desirable. Therefore, we have developed a novel non-invasive methodology utilizing exfoliated colonocytes in order to quantify colonic messenger RNAs (mRNAs). Previously we have demonstrated in the rat that intact eukaryotic mRNA can be isolated due… CONTINUE READING
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