Quantification of hepatitis C virus in patients treated with peginterferon-alfa 2a plus ribavirin treatment by COBAS TaqMan HCV test.

@article{Kanda2011QuantificationOH,
  title={Quantification of hepatitis C virus in patients treated with peginterferon-alfa 2a plus ribavirin treatment by COBAS TaqMan HCV test.},
  author={Tatsuo Kanda and Fumio Imazeki and Yutaka Yonemitsu and Shigeru Mikami and Nobuo Takada and Takayoshi Nishino and Motohide Takashi and A Tsubota and Kazuki Kato and Nobuyuki Sugiura and Akinobu Tawada and S Wu and Toshiyuki Tanaka and Shingo Nakamoto and Rintarou Mikata and Masahiro Tada and Tsutomu Chiba and Tomoko Kurihara and Makoto Arai and Keiichi Fujiwara and Fumihiko Kanai and Osamu Yokosuka},
  journal={Journal of viral hepatitis},
  year={2011},
  volume={18 7},
  pages={e292-7}
}
Extremely low levels of serum hepatitis C virus (HCV) RNA can be detected by COBAS TaqMan HCV test. To investigate whether the COBAS TaqMan HCV test is useful for measuring rapid virological response (RVR) and early virological response (EVR) to predict sustained virological response (SVR), we compared the virological response to PEG-IFN-alfa 2a plus RBV in 76 patients infected with HCV genotype 1 when undetectable HCV RNA by the COBAS TaqMan HCV test was used, with those when below 1.7 log IU… CONTINUE READING

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